Xencor

Xencor engineers antibody Fc domains and multispecifics for enhanced function in cancer and autoimmune indications using its XmAb platform. It focuses on modulating immune responses through validated mechanisms. In comparison, Abalone Bio targets upstream GPCR activation with activity-first discovery at unprecedented scale. Xencor's engineering excels post-discovery but does not match Abalone Bio's ability to find rare functional hits via 100M assays or activity-powered AI for new targets.